MAPK cascade model from Huang and Ferrell (1996) Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 93, 10078-83
This COPASI file simulates a time course and includes a network diagram that can be used to visualize the results (under Model/Biochemical/Diagrams).
This model was altered trivially from the original in Biomodels (BIOMD0000000009), by renaming the species "MAPKKK activator" to E1 and "MAPKKK inactivator" to E2, to conform with the notation of the original paper. The diagram was constructed with SBW's Network Layout tool.
This model originated from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2008 The BioModels Team. For more information see the terms of use.